Sodium Methoxide → HCID 18316937, compound

HRID 276108Notes

Reaction equation

HRID 276108 reaction equation
CC1C=CC(S(O[N:12]=[C:13]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)[CH3:14])(=O)=O)=CC=1.C[O-].[Na+]>CO>[N:12]1[CH2:14][C:13]=1[C:15]1[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 85394088HCID 85394088, compound

Product 1

HCID 18316937HCID 18316937, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

100 g of 1-(3-pyridinyl)-ethanone O-[(4-methylphenyl)sulphonyl]-oxime is introduced at 20° C. under a nitrogen atmosphere into a solution containing 400 ml of anhydrous methanol and 23.45 g of sodium methylate. Agitation is carried out for 2 hours at 20˜22° C. and a suspension containing the sought product is obtained.

Workup

  1. additiona suspension containing the sought product
  2. customis obtained

Sources & evidence

ORD record
ord-efaf125244ff4aa980cb0bc15a95ac5e
Source dataset
uspto-grants-2002_03
Patent number
US06353108B1

Reaction notes

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