1-Bromo-2-methylpropane → 2-(2-Methyl-4-nitrophenylimino)-3-isobutyl-5,5-dimethyl-1,3-thiazolidine

HRID 276527Notes

Reaction equation

HRID 276527 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[N:11]=[C:12]1[NH:16][CH2:15][C:14]([CH3:18])([CH3:17])[S:13]1.[CH2:19](Br)[CH:20]([CH3:22])[CH3:21]>>[CH3:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[N:11]=[C:12]1[N:16]([CH2:19][CH:20]([CH3:22])[CH3:21])[CH2:15][C:14]([CH3:18])([CH3:17])[S:13]1

Participants

3

Reactant 2

HCID 65551-Bromo-2-methylpropaneHCID 178428744HCID 178428744, compound

Product 1

HCID 183162372-(2-Methyl-4-nitrophenylimino)-3-isobutyl-5,5-dimethyl-1,3-thiazolidine

Procedure

2-Methyl-2-hydroxypropylamine was reacted with SOCl2 followed by 2-methyl-4-nitrophenyl isothiocyanate according to Method C1a to afford 2-(2-methyl-4-nitrophenylimino)-5,5-dimethyl-1,3-thiazolidine. The thiazolidine was reacted with isobutyl bromide according to Method D2g to afford 2-(2-methyl-4-nitrophenylimino)-3-isobutyl-5,5-dimethyl-1,3-thiazolidine.

Sources & evidence

ORD record
ord-ca5b5cc8c45943699b38e3393ed9b4ad
Source dataset
uspto-grants-2002_03
Patent number
US06353006B1

Reaction notes

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