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HRID27677

反应详情

EQUATION

反应方程式

HRID 27677 的结构方程式

REACTANTS

反应物

4
结构：NC=O
HCID713

Formamide

CH3NO

结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：CCN(CC)c1ccc(N=Nc2c(Br)cc([N+](=O)[O-])cc2[N+](=O)[O-])c(NC(C)=O)c1
HCID104287

N-(2-((2-Bromo-4,6-dinitrophenyl)azo)-5-(diethylamino)phenyl)acetamide

C18H19BrN6O5

结构：CC(=O)[O-].[Na+]
HCID517045

Sodium Acetate

C2H3NaO2

PRODUCTS

生成物

1
结构：CCN(CC)c1ccc(N=Nc2c(C#N)cc([N+](=O)[O-])cc2[N+](=O)[O-])c(NC(C)=O)c1
HCID90383

N-(2-((2-Cyano-4,6-dinitrophenyl)azo)-5-(diethylamino)phenyl)acetamide

C19H19N7O5

收率 88%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Cu][I]
催化剂HCID24350

Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

CuI

结构：CCCCOC(C)=O
溶剂HCID31272

Butyl acetate

C6H12O2

CONDITIONS

反应条件

温度
110 °C

PROCEDURE

实验过程

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino) azobenzene (479 parts), copper (I) iodide (19 parts), anhydrous sodium acetate (246 parts), formamide (180 parts), acetic anhydride (408 parts) and n-butyl acetate (2190 parts) are mixed together and heated, with stirring, to 110° C. during 15 minutes. The temperature is maintained at 110° for 30 to 50 minutes, when a solid is suddenly precipitated from the reaction mixture, indicating completion of the reaction. The mixture is allowed to cool to room temperature and the product is collected, washed with ethanol to remove residual n-butyl acetate and dried. 2-Cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene is obtained in 88% yield and requires no purification.

WORKUP

后处理

  1. temperatureheated
  2. temperatureThe temperature is maintained at 110° for 30 to 50 minutes
  3. customwhen a solid is suddenly precipitated from the reaction mixture
  4. customcompletion of the reaction
  5. temperatureto cool to room temperature
  6. customthe product is collected
  7. washwashed with ethanol
  8. customto remove residual n-butyl acetate
  9. customdried