反应详情

Ethyl 5-amino-1-phenyl-1,2,3-triazole-4-carboxylate (3.13 g; 0.0135 mole) was stirred at reflux with a solution of sodium (0.31 g; 0.135 atom) in ethanol (20 ml) for 3 hrs. and the mixture evaporated to dryness. The residual solid was dissolved in warm water, acidified and the precipitate filtered off to give 2.622 g (84%) of the title compound of mp 126-127° C. Recrystallisation from 90% ethanol gave material of mp 131-132° C. (lit mp 129-130° C.; O. Dimroth Annalen 364 183 [1909])

1. customand the mixture evaporated to dryness
2. dissolutionThe residual solid was dissolved in warm water
3. filtrationthe precipitate filtered off