Sodium Hydroxide → HCID 178426378, compound

HRID 27690Notes

Reaction equation

HRID 27690 reaction equation
[C:1]1([CH3:18])[CH:6]=[CH:5][C:4]([NH:7][C:8]2[N:9]=[N:10][NH:11][C:12]=2[C:13]([O:15]CC)=[O:14])=[CH:3][CH:2]=1.[OH-].[Na+]>CC(C)=O.O>[C:1]1([CH3:18])[CH:2]=[CH:3][C:4]([NH:7][C:8]2[N:9]=[N:10][NH:11][C:12]=2[C:13]([OH:15])=[O:14])=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178470433Ethyl 4-(p-tolylamino)-1,2,3-triazole-5-carboxylate

Product 1

HCID 178426378HCID 178426378, compoundYield 96.6%

Reagents, catalysts & solvents 1

HCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

Hydrolysis of ethyl 4-(p-tolylamino)-1,2,3-triazole-5-carboxylate (4.5 g) with aqueous sodium hydroxide as described in example 1c, afforded 3.85 g (96%) of acid of mp (acetone-water) 144° C., (Found; C, 55.32; H, 4.86; N, 25.64; C10H10N4O2 requires; C, 55.04; H, 4.62; N, 25.77%).

Sources & evidence

ORD record
ord-7a8a62db10d84e3bb41e563a15627eb2
Source dataset
uspto-grants-1980_09
Patent number
US04223032

Reaction notes

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