4-Pyridinecarboxaldehyde → HCID 22629711, compound

HRID 277068Notes

Reaction equation

HRID 277068 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH2:9])[CH:3]=1.C1(C)C=C(C)C=C(C)C=1S(O[NH2:22])(=O)=O.[N:24]1[CH:29]=[CH:28][C:27]([CH:30]=O)=[CH:26][CH:25]=1>>[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]2[N:22]=[C:30]([C:27]3[CH:28]=[CH:29][N:24]=[CH:25][CH:26]=3)[N:9]=[C:4]2[CH:3]=1

Participants

4

Reactant 3

HCID 133894-PyridinecarboxaldehydeHCID 114353934-Bromo-2,6-diaminopyridineHCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine

Product 1

HCID 22629711HCID 22629711, compound

Procedure

The title compound, MS m/e (%): 292 (M++2, 100), was prepared in accordance with the general method of example 63 from 4-bromo-pyridine-2,6-diamine, O-mesitylene-sulfonylhydroxylamine, and 4-pyridinecarboxaldehyde. The purification was performed with reversed phase HPLC eluting with an acetonitrile/water gradient.

Sources & evidence

ORD record
ord-4cb21fc39f1d4ecea4bed85960823882
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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