Salicylaldehyde → HCID 135581582, compound

HRID 277070Notes

Reaction equation

HRID 277070 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH2:9])[CH:3]=1.C1(C)C=C(C)C=C(C)C=1S(O[NH2:22])(=O)=O.[CH:24](=O)[C:25]1[C:26](=[CH:28][CH:29]=[CH:30][CH:31]=1)[OH:27]>>[NH2:8][C:6]1[N:5]2[N:22]=[C:24]([C:25]3[CH:31]=[CH:30][CH:29]=[CH:28][C:26]=3[OH:27])[N:9]=[C:4]2[CH:3]=[C:2]([Br:1])[CH:7]=1

Participants

4

Reactant 3

HCID 6998SalicylaldehydeHCID 114353934-Bromo-2,6-diaminopyridineHCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine

Product 1

HCID 135581582HCID 135581582, compound

Procedure

The title compound, MS m/e (%): 307 (M+2, 100), was prepared in accordance with the general method of example 63 from 4-bromo-pyridine-2,6-diamine, O-mesitylene-sulfonylhydroxylamine, and salicylaldehyde. The purification was performed with reversed phase HPLC eluting with an acetonitrile/water gradient.

Sources & evidence

ORD record
ord-f6480a4efcab44078ac53e895d56838c
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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