2-Methoxybenzaldehyde → HCID 18313580, compound

HRID 277071Notes

Reaction equation

HRID 277071 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH2:9])[CH:3]=1.C1(C)C=C(C)C=C(C)C=1S(O[NH2:22])(=O)=O.[CH:24](=O)[C:25]1[C:26]([O:31][CH3:32])=[CH:27][CH:28]=[CH:29][CH:30]=1>>[Br:1][C:2]1[CH:7]=[C:6]([NH2:8])[N:5]2[N:22]=[C:24]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=3[O:31][CH3:32])[N:9]=[C:4]2[CH:3]=1

Participants

4

Reactant 3

HCID 86582-MethoxybenzaldehydeHCID 114353934-Bromo-2,6-diaminopyridineHCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine

Product 1

HCID 18313580HCID 18313580, compound

Procedure

The title compound, MS m/e (%): 321 (M++2, 100), was prepared in accordance with the general method of example 63 from 4-bromo-pyridine-2,6-diamine, O-mesitylene-sulfonylhydroxylamine, and o-anisaldehyde. The purification was performed with reversed phase HPLC eluting with an acetonitrile/water gradient.

Sources & evidence

ORD record
ord-124c68a2cdd14a12915a8b623646d88c
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

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