1H-1,2,4-Triazole → 7-Pyridin-2-yl-2-[1,2,4]triazol-1-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277123Notes

Reaction equation

HRID 277123 reaction equation
CS([C:4]1[N:19]=[C:7]2[CH:8]=[C:9]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)[CH:10]=[C:11]([NH2:12])[N:6]2[N:5]=1)=O.N12CCCN=C1CCCCC2.[NH:31]1[CH:35]=[N:34][CH:33]=[N:32]1>>[N:14]1[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=1[C:9]1[CH:10]=[C:11]([NH2:12])[N:6]2[N:5]=[C:4]([N:31]3[CH:35]=[N:34][CH:33]=[N:32]3)[N:19]=[C:7]2[CH:8]=1

Participants

4

Reactant 3

HCID 92571H-1,2,4-TriazoleHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 226297032-Methanesulfinyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Product 1

HCID 183136587-Pyridin-2-yl-2-[1,2,4]triazol-1-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

Procedure

The title compound, MS m/e (%):279 (M+H+,100), was prepared in accordance with the method of example 339b) from 2-methanesulfinyl-7-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine and 1,8-diazabicyclo[5.4.0]undec-7-en in 1,2,4-triazole at 130° C.

Sources & evidence

ORD record
ord-04df69685f974827a6afc6ea3b17c387
Source dataset
uspto-grants-2002_03
Patent number
US06355653B1

Reaction notes

Loading…