p-Toluidine → HCID 18546320, compound

HRID 277222Notes

Reaction equation

HRID 277222 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[NH2:12][C:13]1[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=1>>[CH3:19][C:16]1[CH:17]=[CH:18][C:13]([NH:12][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 7813p-ToluidineHCID 877542-Bromophenylacetic acid

Product 1

HCID 18546320HCID 18546320, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with p-toluidine to yield 2-[(4-methylphenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-68cca93ea14d47f1a88aa8e39d763f81
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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