3-Chloro-2-methylaniline → Phenylacetic Acid

HRID 277226Notes

Reaction equation

HRID 277226 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].CC1C(Cl)=CC=CC=1N>>[C:3]1([CH2:8][C:9]([OH:11])=[O:10])[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1

Participants

3

Reactant 2

HCID 68943-Chloro-2-methylanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 999Phenylacetic Acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2-methyl-3-chloroaniline to yield 2-[2-methyl-3-chlorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-fceeb16d6431463f8e452bfd315a81de
Source dataset
uspto-grants-2002_03
Patent number
US06355680B1

Reaction notes

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