HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 18685245, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 22625966 | HCID 22625966 | — |
| Reactant | HCID 22625974 | HCID 22625974 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 18685245 | HCID 18685245 | — |
Reaction Steps
To a solution of 11 (0.060 g, 0.109 mmol) in 10 ml of CHCl3 was added N-(3-amino)propyl-4-(2-cyanophenyl)-4-cyanopiperidine dihydrochloride (Example 1) and diisopropyl ethylamine (0.057 mL, 0.329 mmol). The resulting solution was stirred for 2 hours and the crude material purified by PCTLC (5% MeOH in CHCl3/2%NH4OH) affording the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358959B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-eed295a2ef0c46b1b660b0d20e429d4d |
| Source note | uspto-grants-2002_03 |