4-Toluenesulfonyl chloride → 5-Phenylpentyl p-toluenesulfonate

HRID 277896Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 277896
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(N(CC)CC)C.[C:20]1([CH3:30])[CH:25]=[CH:24][C:23]([S:26](Cl)(=[O:28])=[O:27])=[CH:22][CH:21]=1>C(Cl)Cl>[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][S:26]([C:23]2[CH:24]=[CH:25][C:20]([CH3:30])=[CH:21][CH:22]=2)(=[O:28])=[O:27])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

5

Edukt 3

HCID 73974-Toluenesulfonyl chlorideHCID 8471TriethylamineHCID 615235-Phenyl-1-pentanol

Produkt 1

HCID 152495035-Phenylpentyl p-toluenesulfonateAusbeute 102,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of 5-phenyl-1-pentanol (3.28 g, 20 mmoles) and triethylamine (6.13 ml, 44 mmoles) in CH2Cl2 (35 ml) under N2, p-toluen-sulphonyl chloride (4.19 g, 22 mmoles) was added and then put under stirring up to room temperature for 1 night. The mixture was washed with water, NaHCO3 and 5% HCl, anhydrified and brought to dryness to give 6.55 g of the title compound (yield: 100%).

Aufarbeitung

  1. washThe mixture was washed with water, NaHCO3 and 5% HCl

Quellen und Nachweise

ORD-Eintrag
ord-02b648232c2e4188946f7fce31d6ec3d
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06358973B1

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