HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → HCID 86757870, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | HCID 22626827 | HCID 22626827 | — |
| Reactant | 3-Cyclopentyl-2-(3-methoxy-phenyl)-propylamine | HCID 22626851 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86757870 | HCID 86757870 | 98.3% |
Reaction Steps
By working in a way similar to that described in example 4 but using (3,5-dichloro-pyridin-4-yl)-acetic acid (1.94 g, 9.43 mmoles), carbonyldiimidazole (1.68 g, 10.373 mmoles), THF (30 ml) and 3-cyclopentyl-2-(3-methoxy-phenyl)-propylamine (2.2 g, 9.43 mmoles), obtained as described in example 8, 3.35 g of the title compound were obtained (yield: 98.3%), m.p.: 106-107° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358973B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-94b7c831945a439ea577e74e2411a335 |
| Source note | uspto-grants-2002_03 |