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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 277899Generated: October 30, 2026

1,1'-Carbonyldiimidazole → HCID 86757870, compound

https://huagongshe.com/reaction/277899

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 22626827HCID 22626827—
Reactant3-Cyclopentyl-2-(3-methoxy-phenyl)-propylamineHCID 22626851—
SolventTetrahydrofuranHCID 8028—
ProductHCID 86757870HCID 8675787098.3%

Reaction Steps

By working in a way similar to that described in example 4 but using (3,5-dichloro-pyridin-4-yl)-acetic acid (1.94 g, 9.43 mmoles), carbonyldiimidazole (1.68 g, 10.373 mmoles), THF (30 ml) and 3-cyclopentyl-2-(3-methoxy-phenyl)-propylamine (2.2 g, 9.43 mmoles), obtained as described in example 8, 3.35 g of the title compound were obtained (yield: 98.3%), m.p.: 106-107° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06358973B1
Source datasetuspto-grants-2002_03
ORD IDord-94b7c831945a439ea577e74e2411a335
Source noteuspto-grants-2002_03