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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 277902Generated: October 30, 2026

1,1'-Carbonyldiimidazole → HCID 22626826, compound

https://huagongshe.com/reaction/277902

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 22626827HCID 22626827—
ReactantHCID 22626852HCID 22626852—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22626826HCID 2262682684.6%

Reaction Steps

By working in a way similar to that described in example 4 but using (3,5-dichloro-pyridin-4-yl)-acetic acid (1.65 g, 8.026 mmoles), carbonyldiimidazole (1.43 g, 8.829 mmoles), THF (25 ml) and 2-(3-methoxy-phenyl)-8-phenyl-octylamine (2.5 g, 8.026 mmoles), obtained as described in example 13, 3.39 g of the title compound were obtained (yield: 84.6%), m.p.: 97-98° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06358973B1
Source datasetuspto-grants-2002_03
ORD IDord-d23245bb462343c4bc1ed561d00ed4a4
Source noteuspto-grants-2002_03