HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 2-Fluoro-6-(trifluoromethyl)mandelic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 2-Fluoro-6-(trifluoromethyl)benzaldehyde | HCID 521933 | — |
| Product | 2-Fluoro-6-(trifluoromethyl)mandelic acid | HCID 22626722 | — |
Reaction Steps
The 2-fluoro-6-trifluoromethylbenzaldehyde (48.4 g, 252 mmol) was converted to product in a manner substantially analogous to Preparation 59 to yield 49.7 g. (84%). EA, MS(FD).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358971B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-f7eb1ebf36f54f708b829636243b05de |
| Source note | uspto-grants-2002_03 |