HCID 9846344, compound → HCID 22626660, compound

HRID 277936Notes

Reaction equation

HRID 277936 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[C:27]([F:29])[CH:26]=[C:25]([F:30])[CH:24]=1)=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:24]=[C:25]([F:30])[CH:26]=[C:27]([F:29])[CH:28]=1

Participants

3

Reactant 1

HCID 9846344HCID 9846344, compound

Product 1

HCID 22626660HCID 22626660, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(3,5-difluorophenyl)-6-benzoyl-imidazo[1,2-a]pyridine (10.2 g, 22.9 mmol) was converted to product in a manner substantially analogous to Example 56 to yield 4.93 g. (61.6%). EA, MS(FD).

Workup

  1. customto yield 4.93 g

Sources & evidence

ORD record
ord-90549c3ddbd043cbb6b8ec251ac9882c
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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