HCID 9847011, compound → HCID 18685707, compound

HRID 277937Notes

Reaction equation

HRID 277937 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][CH:24]=1)=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 1

HCID 9847011HCID 9847011, compound

Product 1

HCID 18685707HCID 18685707, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-napthyl-6-benzoyl-imidazo[1,2-a]pyridine (8.25 g, 18.0 mmol) was converted to product in a manner substantially analogous to Example 56 to yield 4.73 g. (73%). EA, MS(FD).

Workup

  1. customto yield 4.73 g

Sources & evidence

ORD record
ord-8c4c8bcfe5044335bc48b4f59cf65579
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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