HCID 9933194, compound → HCID 22626644, compound

HRID 277938Notes

Reaction equation

HRID 277938 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:24]=1[F:30])=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:24]=1[F:30]

Participants

3

Reactant 1

HCID 9933194HCID 9933194, compound

Product 1

HCID 22626644HCID 22626644, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(2,5-difluorophenyl)-6-benzoyl-imidazo[1,2-a]pyridine (12.1 g, 27.1 mmol) was converted to product in a manner substantially analogous to Example 56 to yield 6.10 g. (64.6%) EA, MS (FD).

Workup

  1. customto yield 6.10 g

Sources & evidence

ORD record
ord-71775e7d278749dbbb3055dd3098a62f
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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