HCID 22626735, compound → HCID 22626665, compound

HRID 277939Notes

Reaction equation

HRID 277939 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[C:28]([F:29])=[CH:27][CH:26]=[CH:25][C:24]=1[F:30])=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[C:24]([F:30])=[CH:25][CH:26]=[CH:27][C:28]=1[F:29]

Participants

3

Reactant 1

HCID 22626735HCID 22626735, compound

Product 1

HCID 22626665HCID 22626665, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(2,6-difluorophenyl)-6-benzoyl-imidazo[1,2-a]pyridine (6.01 g, 13.5 mmol) was converted to product in a manner substantially analogous to Example 56 to yield 3.42 9. (72.6%). EA, MS(FD).

Workup

  1. customto yield 3.42 9

Sources & evidence

ORD record
ord-40a6c8a3da2942b68bc9f0ec00a1afe2
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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