HCID 22626724, compound → HCID 22626767, compound

HRID 277940Notes

Reaction equation

HRID 277940 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][CH:24]=1)=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:24]=[CH:25][C:26]([C:29]([F:32])([F:30])[F:31])=[CH:27][CH:28]=1

Participants

3

Reactant 1

HCID 22626724HCID 22626724, compound

Product 1

HCID 22626767HCID 22626767, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(4-trifluoromethylphenyl)-6-benzoyl-imidazo[1,2-a]pyridine (10.1 g, 21.2 mmol) was converted to product in a manner substantially analogous to Example 56 to yield 4.43 g. (54.8%). EA, MS(FD).

Workup

  1. customto yield 4.43 g

Sources & evidence

ORD record
ord-516123b2f6ec474b86823c556564c75c
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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