HCID 9888749, compound → HCID 22626636, compound

HRID 277942Notes

Reaction equation

HRID 277942 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([F:29])[CH:24]=1)=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([F:29])[CH:24]=1

Participants

3

Reactant 1

HCID 9888749HCID 9888749, compound

Product 1

HCID 22626636HCID 22626636, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(3-fluorophenyl)-6-benzoyl-imidazo[1,2-a]pyridine (14.3 g, 33.6 mmol) was converted to product in a manner substantially analogous to Example 56 to yield 8.30 g. (74.7%). EA, MS(FD).

Workup

  1. customto yield 8.30 g

Sources & evidence

ORD record
ord-b1f2324ac1c843e1a8f42243a2d71c43
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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