HCID 22626698, compound → HCID 22626755, compound
Reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:22]=1[CH2:23][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The 2-trifluoroacetamido-3-benzyl-6-benzoyl-imidazo[1,2-a]pyridine (2.14 g, 5.06 mmol) was converted to product in a manner substantially analogous to Example 56 to yield 1.29 g. (78.2%). EA, MS(FD).
Workup
- customto yield 1.29 g
Sources & evidence
- ORD record
- ord-5bbaaba8a4fd41cd947252eeceea7b19
- Source dataset
- uspto-grants-2002_03
- Patent number
- US06358971B1
Reaction notes
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