HCID 9912221, compound → HCID 22626723, compound

HRID 277947Notes

Reaction equation

HRID 277947 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][C:26]([F:29])=[C:25]([F:30])[C:24]=1[F:31])=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][C:26]([F:29])=[C:25]([F:30])[C:24]=1[F:31]

Participants

3

Reactant 1

HCID 9912221HCID 9912221, compound

Product 1

HCID 22626723HCID 22626723, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(2,3,4-trifluorophenyl)-6-benzoyl-imidazo[1,2-a]pyridine (8.43 g, 18.2 mmol) was converted to product in a manner substantially analogous to Example 67 to yield 5.82 g. (87%). EA, MS(FD).

Workup

  1. customto yield 5.82 g

Sources & evidence

ORD record
ord-43bb6777d52243c28dcf2e1a48d8fcbb
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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