HCID 9955089, compound → HCID 22626656, compound

HRID 277950Notes

Reaction equation

HRID 277950 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[Cl:29])=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[Cl:29]

Participants

3

Reactant 1

HCID 9955089HCID 9955089, compound

Product 1

HCID 22626656HCID 22626656, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(2-chlorophenyl)-6-benzoyl-imidazo[1,2-a]pyridine (10.8 g, 24.2 mmol) was converted to product in a manner substantially analogous to Example 67 to yield 7.45 g. (88.5%). EA, MS(FD).

Workup

  1. customto yield 7.45 g

Sources & evidence

ORD record
ord-02e581d317824e5fa1486b65d6cfdac1
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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