HCID 9935521, compound → HCID 22626624, compound

HRID 277954Notes

Reaction equation

HRID 277954 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][C:24]=1[F:33])=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[C:23]1[CH:28]=[CH:27][C:26]([C:29]([F:31])([F:30])[F:32])=[CH:25][C:24]=1[F:33]

Participants

3

Reactant 1

HCID 9935521HCID 9935521, compound

Product 1

HCID 22626624HCID 22626624, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(2-fluoro-4-trifluoromethylphenyl)-6-benzoyl-imidazo[1,2-a]pyridine (8.03 g, 16.2 mmol) was converted to product in a manner substantially analogous to Example 67 to yield 6.00 g. (92.8%). EA, MS(FD).

Workup

  1. customto yield 6.00 g

Sources & evidence

ORD record
ord-134c8754f6274de39c5b9e6d78ae21bc
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

Loading…