HCID 22626737, compound → HCID 22626619, compound

HRID 277958Notes

Reaction equation

HRID 277958 reaction equation
FC(F)(F)C(NC1N=C2C=CC(C(=O)C3C=CC=CC=3)=CN2C=1C1C(F)=C(F)C(F)=C(F)C=1F)=O.FC(F)(F)C([NH:40][C:41]1[N:42]=[C:43]2[CH:48]=[CH:47][C:46]([C:49](=[O:56])[C:50]3[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=3)=[CH:45][N:44]2[C:57]=1[C:58]1[C:63]([C:64]([F:67])([F:66])[F:65])=[CH:62][CH:61]=[CH:60][C:59]=1[F:68])=O>CC(=O)OCC>[NH2:40][C:41]1[N:42]=[C:43]2[CH:48]=[CH:47][C:46]([C:49](=[O:56])[C:50]3[CH:51]=[CH:52][CH:53]=[CH:54][CH:55]=3)=[CH:45][N:44]2[C:57]=1[C:58]1[C:63]([C:64]([F:66])([F:65])[F:67])=[CH:62][CH:61]=[CH:60][C:59]=1[F:68]

Participants

3

Reactant 1

HCID 22626737HCID 22626737, compound

Product 1

HCID 22626619HCID 22626619, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(2-fluoro-6-trifluoromethylphenyl)-6-benzoyl-imidazo[1,2-a]pyridine 2-trifluoroacetamido-3-(2,3,4,5,6-pentafluorophenyl)-6-benzoyl-imidazo[1,2-a]pyridine (1.80 g, 3.64 mmol) was converted to product in a manner substantially analogous to Example 67 to yield 1.28 g. (88.3%). EA, MS(FD).

Workup

  1. customto yield 1.28 g

Sources & evidence

ORD record
ord-16611be7ce4e404d9e0c15ef4cf07e42
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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