HCID 22626700, compound → HCID 22626632, compound

HRID 277962Notes

Reaction equation

HRID 277962 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[CH2:23][CH:24]([CH3:26])[CH3:25])=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:22]=1[CH2:23][CH:24]([CH3:26])[CH3:25]

Participants

3

Reactant 1

HCID 22626700HCID 22626700, compound

Product 1

HCID 22626632HCID 22626632, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-isobutyl-6-benzoyl-imidazo[1,2-a]pyridine (2.37 g, 6.09 mmol) was converted to product in a manner substantially analogous to Example 67 to yield 1.49 g. (83.5%). EA, MS(FD).

Workup

  1. customto yield 1.49 g

Sources & evidence

ORD record
ord-024470ca88554404857e540e84b62147
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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