HCID 22626681, compound → HCID 22626769, compound

HRID 277963Notes

Reaction equation

HRID 277963 reaction equation
FC(F)(F)C([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:22])[C:15]3[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=3)=[CH:10][N:9]2[C:23]=1[C:24]1[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][C:25]=1[F:34])=O>CC(=O)OCC>[NH2:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:22])[C:15]3[CH:16]=[CH:17][C:18]([F:21])=[CH:19][CH:20]=3)=[CH:10][N:9]2[C:23]=1[C:24]1[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:31])[F:32])=[CH:26][C:25]=1[F:34]

Participants

3

Reactant 1

HCID 22626681HCID 22626681, compound

Product 1

HCID 22626769HCID 22626769, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The 2-trifluoroacetamido-3-(2-fluoro-4-trifluoromethylphenyl)-6-(4-fluorobenzoyl)-imidazo[1,2-a]pyridine (6.75 g, 13.2 mmol) was converted to product in a manner substantially analogous to Example 67 to yield 4.66 g. (85%). EA, MS(FD).

Workup

  1. customto yield 4.66 g

Sources & evidence

ORD record
ord-53ccd7e8bdb34e0391f015878106c645
Source dataset
uspto-grants-2002_03
Patent number
US06358971B1

Reaction notes

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