Isobutyryl chloride → HCID 22627219, compound

HRID 278078Notes

Reaction equation

HRID 278078 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[C:6]([C:11]([O:13][CH3:14])=[O:12])[CH:5]=2.[C:15](Cl)(=[O:19])[CH:16]([CH3:18])[CH3:17]>>[C:15]([C:10]1[C:9]2[C:4](=[CH:5][C:6]([C:11]([O:13][CH3:14])=[O:12])=[CH:7][CH:8]=2)[NH:3][C:2]=1[CH3:1])(=[O:19])[CH:16]([CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 62325Isobutyryl chlorideHCID 11435419HCID 11435419, compound

Product 1

HCID 22627219HCID 22627219, compound

Procedure

Methyl 3-isobutyryl-2-methylindole-6-carboxylate (142 mg) was prepared from methyl 2-methylindole-6-carboxylate (305 mg) and isobutyryl chloride (0.47 ml) in a similar manner to that of Preparation 1 (5).

Sources & evidence

ORD record
ord-2049718fa2144d7fa6e00125722f78c1
Source dataset
uspto-grants-2002_03
Patent number
US06358992B1

Reaction notes

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