Isobutyryl chloride → HCID 22627250, compound

HRID 278080Notes

Reaction equation

HRID 278080 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[NH:5][C:6]2[C:11]([CH:12]=1)=[CH:10][CH:9]=[C:8]([C:13]([O:15][CH3:16])=[O:14])[CH:7]=2.[C:17](Cl)(=[O:21])[CH:18]([CH3:20])[CH3:19]>>[C:17]([C:12]1[C:11]2[C:6](=[CH:7][C:8]([C:13]([O:15][CH3:16])=[O:14])=[CH:9][CH:10]=2)[NH:5][C:4]=1[CH2:3][O:2][CH3:1])(=[O:21])[CH:18]([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 62325Isobutyryl chlorideHCID 22627201HCID 22627201, compound

Product 1

HCID 22627250HCID 22627250, compound

Procedure

Methyl 3-isobutyryl-2-methoxymethylindole-6-carboxylate (146 mg) was prepared from methyl 2-methoxymethylindole-6-carboxylate (396 mg) and isobutyryl chloride (0.53 ml) in a similar manner to that of Preparation 1 (5).

Sources & evidence

ORD record
ord-9db3364f12d34c1db978e90ba1e1bd65
Source dataset
uspto-grants-2002_03
Patent number
US06358992B1

Reaction notes

Loading…