HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → Hydrogen Bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-(3-Methoxyphenyl)-1-phenylpropylamine | HCID 22627103 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Hydrogen Bromide | HCID 260 | — |
| Product | 3-(3-Amino-3-phenylpropyl)phenol | HCID 22627098 | — |
Reaction Steps
A mixture of the product from Step C (920 mg), HOAc (2 mL) and 48% HBr (3 mL) was stirred while heating at reflux. After 2-3 hours, the solution was concentrated in vacuo to provide a pale beige sticky solid which was triturated with Et2O. Removal of residual solvents in vacuo provided the titled product hydrobromide as a pale beige froth.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06358985B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-0744501ef49e4ab5b29e01ccf689d3af |
| Source note | uspto-grants-2002_03 |