反应详情

A mixture of the product from Step C (920 mg), HOAc (2 mL) and 48% HBr (3 mL) was stirred while heating at reflux. After 2-3 hours, the solution was concentrated in vacuo to provide a pale beige sticky solid which was triturated with Et2O. Removal of residual solvents in vacuo provided the titled product hydrobromide as a pale beige froth.

1. temperaturewhile heating
2. temperatureat reflux
3. concentrationthe solution was concentrated in vacuo
4. customto provide a pale beige sticky solid which
5. customwas triturated with Et2O
6. customRemoval of residual solvents in vacuo