1-Chloro-4-(chloromethyl)benzene → HCID 784418, compound

HRID 278292Notes

Reaction equation

HRID 278292 reaction equation
[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[Cl:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13]Cl)=[CH:11][CH:10]=1>>[Cl:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13][N:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 77231-Chloro-4-(chloromethyl)benzeneHCID 8113Diethanolamine

Product 1

HCID 784418HCID 784418, compound

Procedure

2-[(4-chlorobenzyl)-(2-hydroxy-ethyl)-amino]-ethanol was prepared according to the general method as outlined in Example 1 (Step 4). Starting from diethanolamine (14.3 g, 95 mmol). and 4-chlorobenzyl chloride (10.2 g, 63 mmol). Yield 12.1 g, (84%); yellow oil; MS: 230 (M+H)+

Sources & evidence

ORD record
ord-994c050fe1c94e97b2cd1fc66fd58c1d
Source dataset
uspto-grants-2002_03
Patent number
US06358980B1

Reaction notes

Loading…