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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278421Generated: October 31, 2026

(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuran → 1-(5-Benzyloxy-2,3-dihydro-benzofuran-2-ylmethyl)-4-(4-methoxy-benzyl)-piperidin-4-ol

https://huagongshe.com/reaction/278421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(RS)-5-Benzyloxy-2-bromomethyl-2,3-dihydro-benzofuranHCID 22628347—
Reactant4-[(4-Methoxyphenyl)methyl]piperidin-4-olHCID 22628349—
Product1-(5-Benzyloxy-2,3-dihydro-benzofuran-2-ylmethyl)-4-(4-methoxy-benzyl)-piperidin-4-olHCID 22628395—

Reaction Steps

The title compound MS: m/e=460.2 (M+H+) was prepared from 4-(4-methoxy-benzyl)-piperidin-4-ol and 5-benzyloxy-2-(RS)-bromomethyl-2,3-dihydro-benzofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359138B1
Source datasetuspto-grants-2002_03
ORD IDord-42db4a37e5764a1f93209c98f3a623a7
Source noteuspto-grants-2002_03