HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(Pyridin-4-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 4-(pyridin-4-yl)benzoate | HCID 15294733 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(Pyridin-4-yl)benzoic acid | HCID 1520811 | 86.7% |
Reaction Steps
A mixture of ethyl 4-(4-pyridyl)benzoate (1.0 g), 1 N NaOH (8.8 ml) and ethanol (8.8 ml) was stirred at room temperature for 1 hour and diluted with water, to which was added 1 N hydrochloric acid (8.8 ml) to give the title compound as crystals (0.76 g, 86.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06359134B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-47b8215a62514fafbc02729a6eb96e79 |
| Source note | uspto-grants-2002_03 |