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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278579Generated: October 31, 2026

Hydrochloric Acid → 1-[2-(4-Chlorophenyl)ethynesulfonyl]piperazine hydrochloride

https://huagongshe.com/reaction/278579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1-(Tert-butoxycarbonyl)-4-[2-(4-chlorophenyl)ethynesulfonyl]piperazineHCID 22628062—
SolventEthyl AcetateHCID 8857—
Product1-[2-(4-Chlorophenyl)ethynesulfonyl]piperazine hydrochlorideHCID 22628002182.1%

Reaction Steps

1-(tert-Butoxycarbonyl)-4-[2-(4-chlorophenyl)ethynesulfonyl]piperazine (500 mg) was treated with 4N hydrochloric acid in ethyl acetate to give a colorless solid of the title compound (380 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359134B1
Source datasetuspto-grants-2002_03
ORD IDord-0ea6e2abc8d243388cf9f0006b4d0563
Source noteuspto-grants-2002_03