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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278603Generated: November 2, 2026

Hydrochloric Acid → HCID 18628934, compound

https://huagongshe.com/reaction/278603

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDiethyl EtherHCID 3283—
ReactantHCID 145840730HCID 145840730—
SolventEthyl AcetateHCID 8857—
ProductHCID 18628934HCID 18628934153.5%

Reaction Steps

To 1-(4-tert-butoxycarbonylamidino benzoyl)-4-(6-chloronaphthalene-2-sulfonyl)piperazine (150 mg) was added 4 N hydrochloric acid in ethyl acetate solution (15 ml) and the solution was allowed to stand at room temperature for 5 hours, to which was added ether. The precipitate was filtered, washed with ether and dried to give a colorless solid of the title compound (102 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359134B1
Source datasetuspto-grants-2002_03
ORD IDord-3ac7963cdaac43489866917649e8b98f
Source noteuspto-grants-2002_03