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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278604Generated: October 29, 2026

Hydrochloric Acid → HCID 178479380, compound

https://huagongshe.com/reaction/278604

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDiethyl EtherHCID 3283—
ReactantHCID 178454284HCID 178454284—
SolventEthyl AcetateHCID 8857—
ProductHCID 178479380HCID 178479380171.2%

Reaction Steps

To 1-[4-(2,3-di-tert-butoxycarbonylguanidino)benzoyl]-4-(6-chloronaphthalene-2-sulfonyl)piperazine (295 mg) was added 4 N hydrochloric acid in ethyl acetate solution (20 ml) and the solution was allowed to stand at room temperature for 3 hours, to which was added ether. The precipitate was filtered, washed with ether and dried to give a colorless solid of the title compound (191 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06359134B1
Source datasetuspto-grants-2002_03
ORD IDord-6ee70dde4d7240448b4c33d877ee0f15
Source noteuspto-grants-2002_03