HCID 178453612, 화합물 → HCID 178479225, 화합물

HRID 278624노트

반응식

HRID 278624 반응식
C(OC([NH:8][CH2:9][C@H:10]1[CH2:15][CH2:14][C@H:13]([C:16]([N:18]2[CH2:23][CH2:22][N:21]([S:24]([C:27]3[CH:36]=[CH:35][C:34]4[C:29](=[CH:30][CH:31]=[C:32]([Cl:37])[CH:33]=4)[CH:28]=3)(=[O:26])=[O:25])[CH2:20][CH2:19]2)=[O:17])[CH2:12][CH2:11]1)=O)(C)(C)C>Cl.C(OCC)(=O)C>[ClH:37].[NH2:8][CH2:9][C@H:10]1[CH2:15][CH2:14][C@H:13]([C:16]([N:18]2[CH2:23][CH2:22][N:21]([S:24]([C:27]3[CH:36]=[CH:35][C:34]4[C:29](=[CH:30][CH:31]=[C:32]([Cl:37])[CH:33]=4)[CH:28]=3)(=[O:25])=[O:26])[CH2:20][CH2:19]2)=[O:17])[CH2:12][CH2:11]1

참가 물질

3

반응물 1

HCID 178453612HCID 178453612, 화합물

생성물 1

HCID 178479225HCID 178479225, 화합물

시약·촉매·용매 1

HCID 21866389Hydrogen chloride-ethyl acetate용매

실험 절차

A mixture of 1-(trans-4-tert-butoxycarbonylaminomethylcyclohexane-1-carbonyl)-4-(6-chloronaphthalene-2-sulfonyl)piperazine (0. 7g) and 4 N HCl-ethyl acetate (10 ml) was stirred at room temperature for 1 hour, and the precipitated crystals of the title compound (0.48g) were filtered.

후처리

  1. filtrationthe precipitated crystals of the title compound (0.48g) were filtered

출처 및 근거

ORD 기록
ord-1e1ac8fa1b824492869492b6c0ee0582
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06359134B1

반응 노트

불러오는 중…