Hydrochloric Acid → HCID 135856747, compound

HRID 278871Notes

Reaction equation

HRID 278871 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([CH2:32][CH2:33][CH3:34])[N:5]2[C:10]=1[C:9](=[O:11])[NH:8][C:7]([C:12]1[CH:17]=[C:16]([S:18]([N:21]3[CH2:26][CH2:25][N:24]([CH3:27])[CH2:23][CH2:22]3)(=[O:20])=[O:19])[CH:15]=[CH:14][C:13]=1[O:28][CH2:29][CH2:30][CH3:31])=[N:6]2.[Cl:35]CCl.Cl>CCOCC>[ClH:35].[CH3:1][C:2]1[N:3]=[C:4]([CH2:32][CH2:33][CH3:34])[N:5]2[C:10]=1[C:9](=[O:11])[NH:8][C:7]([C:12]1[CH:17]=[C:16]([S:18]([N:21]3[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]3)(=[O:20])=[O:19])[CH:15]=[CH:14][C:13]=1[O:28][CH2:29][CH2:30][CH3:31])=[N:6]2

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 135856741HCID 135856741, compound

Product 1

HCID 135856747HCID 135856747, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

22 mg (0.045 mmol) of 5-methyl-2-[5-(4-methyl-piperazine-1-sulphonyl)-2-propoxy-phenyl]-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one are dissolved in 2 ml of ether and 1 ml of dichloromethane and admixed with 0.1 ml of a 1M solution of HCl in ether. After 20 minutes, the precipitate is filtered off with suction and dried.

Workup

  1. filtrationthe precipitate is filtered off with suction
  2. customdried

Sources & evidence

ORD record
ord-79a9b9c4f77c4f8a867816eb04c73409
Source dataset
uspto-grants-2002_03
Patent number
US06362178B1

Reaction notes

Loading…