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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 278939Generated: October 28, 2026

Hydrochloric Acid → HCID 18001373, compound

https://huagongshe.com/reaction/278939

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantTetrahydrofuran 2-propanolHCID 22597222—
ProductHCID 18001373HCID 18001373—

Reaction Steps

Part C. A solution of the MOM compound from Part B (1.84 g, 9.38 mmol) was dissolved in 1:1 THF-isopropanol (20 mL), and treated with HCl in dioxane (2.5 mL, 4 N, 10.0 mmol). The reaction was stirred at ambient temperature overnight. Aqueous workup gave sufficiently pure product, 2-(2-hydroxy-4-methylphenyl)ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06362180B1
Source datasetuspto-grants-2002_03
ORD IDord-36d7294ee27e4f91a31ea85d3fb24721
Source noteuspto-grants-2002_03