Hydrochloric Acid → HCID 805603, compound

HRID 279012Notes

Reaction equation

HRID 279012 reaction equation
Cl.C([N:6]1[C:15](=[O:16])[C:14]2[C:17](O[SiH3])=[C:18]([NH2:21])[C:19](C)=[C:12]3[C:13]=2[C:8](=[CH:9][C:10]([NH2:25])=[C:11]3C)[C:7]1=[O:26])(C)(C)C.C([OH:29])C>>[NH2:25][C:10]1[CH:11]=[C:12]2[CH:19]=[C:18]([NH2:21])[CH:17]=[C:14]3[C:13]2=[C:8]([CH:9]=1)[C:7](=[O:26])[N:6]([OH:29])[C:15]3=[O:16]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 137328519HCID 137328519, compound

Product 1

HCID 805603HCID 805603, compound

Procedure

A solution of 1% HCl in ethanol (100 mL) was added to 2-tert-butyldimethyl-silyloxy-5,8-diamino-benzo[de]isoquinoline-1,3-dione (0.4 g, 1.0 mmol, from Example I1) with stirring at room temperature. After 1 hour, the solids formed were filtered, washed with ether, and dried to give 0.2 g of the title compound, mp 329-336° C.;

Workup

  1. customthe solids formed
  2. filtrationwere filtered
  3. washwashed with ether
  4. customdried

Sources & evidence

ORD record
ord-c6837a1aa7a447c18f49b040c92d3f95
Source dataset
uspto-grants-2002_03
Patent number
US06362181B1

Reaction notes

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