HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylsilane → HCID 22624016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylsilane | HCID 12752 | — |
| Reactant | HCID 22623960 | HCID 22623960 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22624016 | HCID 22624016 | 65.6% |
Reaction Steps
Following the procedure of Example 59, 2-allyloxy-5-methyl-7-(pyrrolidin-1-yl)-benzo[de]isoquinoline-1,3-dione (0.55 g, 1.8 mmol, from Example J2), phenylsilane (0.29 g, 2.6 mmol), Pd(PPh3)4 (0.81 g, 0.070 mmol) in CH2Cl2 (40 mL) were reacted to give 0.35 g of the title compound, mp 236-237° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06362181B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-a6ae2e3b839743a29027ea51c2a2ed04 |
| Source note | uspto-grants-2002_03 |