HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22623983, compound → HCID 22624035, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22623983 | HCID 22623983 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 22624035 | HCID 22624035 | 4.6% |
Reaction Steps
A solution of 28 mg (0.72 mmol) of 2-benzyloxy-5-fluoro-6-(pyrrolidin-1-yl)-benzo[de]isoquinoline-1,3-dione (from Example Z3) was hydrogenated over 15 mg of 10% Pd/C at room temperature and atmospheric pressure for 2 hours. Pd/C was removed by filtration, and the filtrate was evaporated to yield 10 mg of the title compound, mp 224-226° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06362181B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-9560652bcf7d4781a591ec2d02f2e071 |
| Source note | uspto-grants-2002_03 |