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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 27944Generated: October 25, 2026

2-(5-Chloro-2-benzothienyl)-3-methylbutanoic acid → 3-(4-Fluorobenzyl)-pyrrolylmethyl 2-(5-chloro-2-benzothienyl)-3-methylbutanoate

https://huagongshe.com/reaction/27944

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Chloro-2-benzothienyl)-3-methylbutanoic acidHCID 54204673—
Reactant3-(4-Fluorobenzyl)-pyrrolylmethyl alcoholHCID 54464622—
SolventDiethyl EtherHCID 3283—
Product3-(4-Fluorobenzyl)-pyrrolylmethyl 2-(5-chloro-2-benzothienyl)-3-methylbutanoateHCID 54419115—

Reaction Steps

The acid chloride of 2-(5-chloro-2-benzothienyl)-3-methylbutanoic acid is reacted with 3-(4-fluorobenzyl)-pyrrolylmethyl alcohol in ether as in Example 20 to give 3-(4-fluorobenzyl)-pyrrolylmethyl 2-(5-chloro-2-benzothienyl)-3-methylbutanoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04224330
Source datasetuspto-grants-1980_09
ORD IDord-b5f20582738f406eb6b3c78ee652cf93
Source noteuspto-grants-1980_09