HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrafluoroisophthalic acid → HCID 10130865, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrafluoroisophthalic acid | HCID 297552 | — |
| Reactant | HCID 178418332 | HCID 178418332 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10130865 | HCID 10130865 | — |
Reaction Steps
20 g of tetrafluoroisophthalic acid are initially charged in 250 ml of THF and, at from 20 to 40° C., admixed with 88 ml of a 3 molar methylmagnesium chloride solution. Customary aqueous work-up (see Example 3) gives 20.1 g of 2,4,5-trifluoro-6-methylisophthalic acid. The purity of the product is 85% by HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06362365B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-77d6ae5fa95046f9b9314c9da16b70f2 |
| Source note | uspto-grants-2002_03 |