Ethyl 3-[4-(benzyloxy)phenyl]-2-ethoxyprop-2-enoate → 3-(4-Benzyloxyphenyl)-2-ethoxypropanoic acid ethyl ester

Beteiligte Stoffe

Reaktionsschritte

3-(4-Benzyloxyphenyl)-2-ethoxyacrylic acid ethyl ester (described in Example 1a) (0.5 g; 1.5 mole) was hydrogenated at atmospheric pressure using rhodium on charcoal as catalyst (5%, 50 mg) in methanol (20 ml). The crude product was purified by chromatography using heptane:ethyl acetate (5:1) as eluent to give 50 mg (yield 10%) of 3-(4-benzyloxyphenyl)-2-ethoxypropanoic acid ethyl ester.

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