HCID 13608310, compound → HCID 13608303, compound

HRID 279790Notes

Reaction equation

HRID 279790 reaction equation
[N:1]([CH:4]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][N:6]([CH2:12][C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[C:5]1=[O:20])=[N+]=[N-].[H][H]>[Pd].C(O)C>[NH2:1][CH:4]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][N:6]([CH2:12][C:13]([O:15][C:16]([CH3:18])([CH3:17])[CH3:19])=[O:14])[C:5]1=[O:20]

Participants

5

Reactant 2

HCID 13608310HCID 13608310, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 13608303HCID 13608303, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Dissolve 9.5 g. 3-azido-1-t-butoxycarbonylmethylperhydroazocin-2-one in 85 ml. ethanol. Hydrogenate at 40 psi hydrogen pressure at room temperature using 1.0 g. 10% palladium on charcoal as catalyst. Filter the reaction and concentrate the filtrate to obtain 3-amino-1-t-butoxycarbonylmethylperhydroazocin-2-one.

Workup

  1. dissolutionDissolve 9.5 g
  2. customat room temperature
  3. filtrationFilter
  4. customthe reaction
  5. concentrationconcentrate the filtrate

Sources & evidence

ORD record
ord-3086a7e1eba74dda82263bc49fc48e51
Source dataset
uspto-grants-1986_05
Patent number
US04587050

Reaction notes

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