Hydrochloric Acid → 2,4-Pyridinediol,1-oxide(9CI)

HRID 279833Notes

Reaction equation

HRID 279833 reaction equation
Cl.[OH:2][C:3]1[CH:8]=[C:7]([OH:9])[CH:6]=[CH:5][N+:4]=1[O-:10]>>[OH:10][N:4]1[CH:5]=[CH:6][C:7]([OH:9])=[CH:8][C:3]1=[O:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178526271HCID 178526271, compound

Product 1

HCID 546940452,4-Pyridinediol,1-oxide(9CI)Yield 30%

Procedure

2,4-Dimethoxypyrid-1-oxide is refluxed together with 20% w/v HCl for 13 hours. On cooling the solution 2,4-dihydroxypyridine-1-oxide is obtained as an orange-white solid (0.42 g, 30%), δ(d6DMSO+trace of D2O), 6.08 (s, 1H), 6.12 (q, 1H), 7.88 (d, 1H).

Sources & evidence

ORD record
ord-fb8c24873eb344cba0305ae75e6f4e19
Source dataset
uspto-grants-1986_05
Patent number
US04587240

Reaction notes

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